The Tie2-agonist Vasculotide rescues mice from influenza virus infection.
Sugiyama MG, Armstrong SM, Wang C, Hwang D, Leong-Poi H, Advani A, Advani S, Zhang H, Szaszi K, Tabuchi A, Kuebler WM, Van Slyke P, Dumont DJ, Lee WL. Sci…
The Tie2-Agonist Vasculotide Protects Lungs from Pneumonia-Induced Barrier Disruption.
Gutbier B, Jiang X, Ehrler C, Mitchell TJ, Weissmann N, Van Slyke P, Dumont DJ, Suttorp N, Witzenrath M. American Thoracic Society 2016 International Conference. http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2016.193.1_MeetingAbstracts.A5458
Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality.
David S, Ghosh CC, Kümpers P, Shushakova N, Van Slyke P, Khankin EV, Karumanchi SA, Dumont D, Parikh SM. Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L851-62. https://www.ncbi.nlm.nih.gov/pubmed/21421750
Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia.
Gutbier B, Jiang X, Dietert K, Ehrler C, Lienau J, Van Slyke P, Kim H, Hoang VC, Maynes JT, Dumont DJ, Gruber AD, Weissmann N, Mitchell TJ, Suttorp N, Witzenrath…